Marijuana And The Growth In Cigarette Alternatives

CALIFORNIA: Tobacco smoking is the leading cause of avoidable death in the US, and chronic exposure to tobacco smoke is related to increased incidences of cancer as well as vascular disease, according to the United States Center for Disease Control. Many substitutes have been created to help individuals quit smoking cigarettes, such as herbal cigarettes, e-cigs, vaping, specialized gum, and many other ways.

Studies found in The Washington Post, pulmonologist Dr. Donald Tashkin, Professor Emeritus at the David Geffen School of Medicine at UCLA, has assumed that there would be a positive association between marijuana use and lung cancer, and that the association would be more positive with heavier use. What they found instead was no connection at all, and even a suggestion of some protective effect.

CV Sciences is currently in development of Cannabidiol-based potential U.S. Food and Drug Administration approved drugs. The company’s pipeline is the CVSI-007, a chewing gum that contains nicotine and synthetic Cannabidiol to support cessation of smokeless tobacco use and addiction. CV Sciences currently has two distinct operations: the Pharmaceuticals and Consumer Products Divisions. These divisions are supported by its medical and scientific advisory board, and advanced art production facilities.

Cannabis And Tobacco Smoke Are Not Equally Carcinogenic

Tobacco has dramatic negative consequences for those who smoke it. In addition to its high addiction potential [1], tobacco is causally associated with over 400,000 deaths yearly in the United States, and has a significant negative effect on health in general [2]. More specifically, over 140,000 lung-related deaths in 2001 were attributed to tobacco smoke [3]. Comparable consequences would naturally be expected from cannabis smoking since the burning of plant material in the form of cigarettes generates a large variety of compounds that possess numerous biological activities [4].

While cannabis smoke has been implicated in respiratory dysfunction, including the conversion of respiratory cells to what appears to be a pre-cancerous state [5], it has not been causally linked with tobacco related cancers [6] such as lung, colon or rectal cancers. Recently, Hashibe et al [7] carried out an epidemiological analysis of marijuana smoking and cancer. A connection between marijuana smoking and lung or colorectal cancer was not observed. These conclusions are reinforced by the recent work of Tashkin and coworkers [8] who were unable to demonstrate a cannabis smoke and lung cancer link, despite clearly demonstrating cannabis smoke-induced cellular damage.

Furthermore, compounds found in cannabis have been shown to kill numerous cancer types including: lung cancer [9], breast and prostate [10], leukemia and lymphoma [11], glioma [12], skin cancer [13], and pheochromocytoma [14]. The effects of cannabinoids are complex and sometimes contradicting, often exhibiting biphasic responses. For example, in contrast to the tumor killing properties mentioned above, low doses of THC may stimulate the growth of lung cancer cells in vitro [15].