Cannabics Pharmaceuticals Announces Positive Results for Pilot Study on Treatment of Cancer Anorexia-Cachexia Syndrome (CACS)

Preliminary findings showed +80% of patients had increase in appetite and 60% +10% weight increase

ISRAEL & MARYLAND: Cannabics Pharmaceuticals, a leader in personalized cannabinoid medicine focused on cancer and its side effects, announced the results of its pilot study to test the efficacy of Cannabics capsules for the treatment of cancer anorexia-cachexia syndrome (CACS) in advanced cancer patients.

Cannabics PharmaceuticalsHeld at Rambam Hospital in Israel, the study is aimed at evaluating the effect of dosage-controlled cannabis capsules on CACS, and more specifically, on weight variations in advanced cancer patients.

Preliminary findings showed that all patients who were involved in the study for the first four and a half months reported an increase in appetite, as well as 83 percent of all those that completed the study. Results also demonstrated a weight increase of over 10 percent for 60 percent of the patients who completed the study. The remaining patients had a stable weight. 50 percent of the patients who completed the study reported pain reduction and sleep improvement.

“Our first clinical trial, led by Dr. Gil Bar-Sela, gave us valuable data on the capsules as a possible oral administration method for palliative care and for our future proprietary cannabinoid compounds,” said Dr. Eyal Ballan, co-founder and chief technology officer of Cannabics Pharmaceuticals. “As we continue to progress in the development of personalized cannabinoid treatments and collect data on compounds, ratios and dosages, we will use the information to incorporate into the design of our next clinical study on cancer patients.”

 

Survey: Oncologists Believe Medical Cannabis To Be Equally Or More Effective Than Conventional Treatments

MASSACHUSETTS: The majority of oncologists believe that the use of medical cannabis is either as effective or more effective than conventional treatments for managing symptoms of cancer, according to survey data published in The Journal of Clinical Oncology.

A team of investigators lead by researchers at The Dana Farber Cancer Clinic randomly surveyed oncologists’ beliefs with regard to the safety and efficacy of cannabis therapy. Sixty-five percent of respondents said that medical marijuana was equally effective or more effective than standard treatments for addressing appetite loss and/or cachexia. The majority of respondents also believed that cannabis was safe and effective as an adjunct treatment for anxiety and pain. Half of respondents said that cannabis was as effective or more effective that conventional medications in treating nausea, and 70 percent viewed marijuana as equally safe or safer than opioids.

The survey also reported that some eighty percent of oncologists had engaged in discussions with their patients about the use of cannabis, although in over half of those instances it was either patients or their families, rather than the oncologists themselves, who prompted the conversation.


For more information, contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, “Medical oncologists’ beliefs, practices, and knowledge regarding marijuana used therapeutically: A nationally representatives survey study,” appears in The Journal of Clinical Oncology.

Clinical Trial: Use Of Herbal Cannabis Safe And Effective In Cancer Patients

ISRAEL: Cannabis administration is associated with the subjective improvement of symptoms in patients with cancer, according to clinical data published in the European Journal of Internal Medicine.

Israeli researchers assessed the safety and efficacy of cannabis in a cohort of over 1,200 cancer patients over a period of six months. Ninety-six percent of patients “reported an improvement in their condition.” Symptomatic improvements included: relief from nausea and vomiting (91 percent), improved sleep (86 percent), decreased anxiety (84 percent), and pain relief (over 50 percent). Nearly half of respondents reported either decreasing or eliminating their use of opioids during the treatment period.

Authors concluded, “Cannabis as a palliative treatment for cancer patients seems to be a well-tolerated, effective, and safe option to help patients cope with the malignancy related symptoms.”

An estimated 30,000 Israeli patients are approved to use medical cannabis, which was legalized by the Ministry of Health in 2007.


For more information, contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, “Prospective analysis of safety and efficacy of medical cannabis in a large unselected population of patients with cancer,” appears in the European Journal of Internal Medicine.

Iowa Medical-Marijuana Proponent Dies Of Cancer

IOWA: One of Iowa’s clearest voices on behalf of legalized medical marijuana has died before she could see her efforts succeed.

Lori Tassin, 44, of Des Moines was a regular presence at the Statehouse last spring, button-holing legislators and testifying about why she and other ill Iowans should have the right to try marijuana. She died Friday of the cancer she’d been fighting for five years.

Tassin contended that many other medications doctors prescribe routinely are vastly more dangerous than marijuana.  At a Senate hearing in February, she unfolded a multi-page insert that came with her chemotherapy drug. The document listed numerous possible side effects of the drug, which she was taking for the tumors that had spread from her lungs to her brain. “Tell me that’s not pretty scary to look at,” she said, holding up the lengthy document for the senators to see.

Stoner Icon Says Hemp Oil To Blame For Tumor

CALIFORNIA: Funnyman and stoner icon Tommy Chong is undergoing surgery to remove a tumour in his rectum in the hope it will end his painful battle with cancer.

The marijuana activist checked into the hospital in Los Angeles on Thursday shortly after appearing on US news show Access Hollywood Live, where he revealed he’s desperate to close out his longtime health issues.

Chong won his battle with prostate cancer in 2012, insisting pot suppositories were a miracle cure, but earlier this year the comedian was diagnosed with rectal cancer – and he believes the hemp oil he used to beat his first cancer may be the cause of his latest crisis.

“When you go into your orifice you’ve got to clinically know what you’re doing with it. I put suppositories up there and I don’t know how they did the oil and so on, and so now I found a laboratory where they test and they make sure that the oil that they give you to inject and everything else is pharmaceutically correct, it’s pure.

How Tommy Chong Beat Cancer With Homegrown Cannabis Medicine

CALIFORNIA:  As the movement for the liberation of cannabis gains momentum, and attitudes toward this relaxing and healing plant evolve, we are witnessing an explosion in innovation around how cannabis is used, both as a medicine and for recreational purposes. Finally overcoming its reputation as a mind-bending, psychoactive drug that makes you stoned, lazy and useless, cannabis is being celebrated for its healing benefits.

In a high profile case of the healing power of CBD’s, famous actor, comedian, and marijuana advocate, Tommy Chong shocked his fans in 2011 when he announced that he had been diagnosed with prostate cancer. As a challenge to the world at that time, he stated his determination to cure his cancer with medical cannabis, and began a journey to do just that. By changing his diet and consuming, CBD rich cannabis oil Tommy beat cancer, which he announced in 2013.

In a recent interview in 2014, Tommy talked in greater detail about how he came to the decision to try hemp oil, and how the process worked for him. Remarkably, he mentions that he had his CBD oil made from plants that he legally grew on his own rooftop, bred to have a high CBD count.

While non-psychoactive CBD rich hemp oil is gaining in renown as a natural medicine, Tommy Chong believes that the high potent sedative and calming effects of the oil, the psychoactive component, is also a very beneficial part of the healing process.  He talks about the nature and benefits of cannabis and why so many of the major cancer treatment centers are ignoring the evidence that cannabis is an effective treatment.

 

Cannabis And Tobacco Smoke Are Not Equally Carcinogenic

Tobacco has dramatic negative consequences for those who smoke it. In addition to its high addiction potential [1], tobacco is causally associated with over 400,000 deaths yearly in the United States, and has a significant negative effect on health in general [2]. More specifically, over 140,000 lung-related deaths in 2001 were attributed to tobacco smoke [3]. Comparable consequences would naturally be expected from cannabis smoking since the burning of plant material in the form of cigarettes generates a large variety of compounds that possess numerous biological activities [4].

While cannabis smoke has been implicated in respiratory dysfunction, including the conversion of respiratory cells to what appears to be a pre-cancerous state [5], it has not been causally linked with tobacco related cancers [6] such as lung, colon or rectal cancers. Recently, Hashibe et al [7] carried out an epidemiological analysis of marijuana smoking and cancer. A connection between marijuana smoking and lung or colorectal cancer was not observed. These conclusions are reinforced by the recent work of Tashkin and coworkers [8] who were unable to demonstrate a cannabis smoke and lung cancer link, despite clearly demonstrating cannabis smoke-induced cellular damage.

Furthermore, compounds found in cannabis have been shown to kill numerous cancer types including: lung cancer [9], breast and prostate [10], leukemia and lymphoma [11], glioma [12], skin cancer [13], and pheochromocytoma [14]. The effects of cannabinoids are complex and sometimes contradicting, often exhibiting biphasic responses. For example, in contrast to the tumor killing properties mentioned above, low doses of THC may stimulate the growth of lung cancer cells in vitro [15].

For patients like me, marijuana is a necessity

DISTRICT OF COLUMBIA: My breast cancer diagnosis at age 26 was an unwelcome and at times harrowing experience. What allowed me to endure the darkest days was the hope that my rigorous treatment — chemotherapy, surgeries and radiotherapy among them — would allow me to once again live a full and healthy life. It’s what propelled me to walk back into the hospital for more treatments.

But then came A/C: The “A” stands for Adriamycin, a drug neon red in color and injected via large syringes by oncology nurses; its apt nicknames are “red devil” and “red death.” That probably should have been the red flag that I wasn’t going to escape without being slightly worse for wear. [Read more…]