WASHINGTON: According to a new study published in the journal Drug and Alcohol Dependence, the hormonal composition of women makes them more sensitive to the effects of marijuana. Oddly, women develop a tolerance to THC much faster than men.
The research project has an odd origin. Psychology professor at Washington State University, Rebecca Craft, noticed one day that many marijuana studies only had male participants. It was that observation that inspired her to gain a better understanding of marijuana and women.
Using lab rats as test subjects, Craft and company discovered that females were 30 percent more sensitive to THC than the males. Craft was also quick to point out that this could also result in females being more likely to experience the negative effects of being stoned such as anxiety and paranoia.
Researchers also saw that the female rodents built up a tolerance to THC much faster than the males. In fact, over time it took larger doses of THC to recreate the same sensations of pain relief for females.